What science can do
Annual Report 和 形成20 f年报
Information 2021
Our Annual Report
澳门第一赌城在线娱乐是一家以科学为主导、以患者为中心的全球性制药公司. 澳门第一赌城在线娱乐孜孜不倦地寻求实现科学的潜力. 在年度报告中，澳门第一赌城在线娱乐报告了2021年在突破科学界限、提供改变生命的药物方面取得的进展.
7月, we completed our l和mark acquisition of Alexion, which established our rare disease capability.
Pascal Soriot, Chief Executive Officer
Strategic overview
澳门第一赌城在线娱乐是一家以科学为主导、以患者为中心的全球制药企业，致力于卓越的研究, 处方药的开发和商业化.
Inspired by our Values 和 what science can do, 澳门第一赌城在线娱乐专注于加速提供改变生活的药物，为患者和社会创造持久的价值.
Accelerate Innovative Science
Accelerating the next wave of new molecular entities, building our capabilities in immunology 和 rare diseases, pursuing new scientific modalities 和 driving R&D生产力.
管道 progression events
321 •
(2020: 36)
1. 根据集团记分卡决定年度奖金. 2021 total includes Alexion.
2. 25 against our Group scorecard for determining annual bonus.
3. 根据集团记分卡决定年度奖金.
Regulatory events
491 •
(2020:53)
1. 根据集团记分卡决定年度奖金. 2021 total includes Alexion.
2. 根据集团记分卡决定年度奖金.
3. 根据集团记分卡决定年度奖金.
Deliver Growth 和 Therapy Area Leadership
通过成功的创新和卓越的商业表现来实现澳门第一赌城在线娱乐的增长和盈利目标, as well as completing the Alexion acquisition.
总收入*
$37,417m •
(2020:$26,617m)
*总收入包括产品销售和协作收入.
Be a Great Place to Work
Contributing to the enterprise 和 to society, with a focus on inclusion 和 diversity, lifelong learning, improving access to healthcare, environmental protection, 和 ethics 和 transparency, as well as delivering our Ambition Zero Carbon programme.
Employee belief that AstraZeneca is a great place to work1
85%
(2020:89%)
1. Source: November Pulse survey for each year.
可持续性 scorecard performance2
83% •
(2020: 93%)
2. 绿色评级=超过70%的类别被评为绿色. Each category consists of several KPIs. We have 14 priority goals. Achievement of <9 is Red; 9 or 10 is Amber; 11 or 12 is Green; 和 13 or 14 is Blue.
• Used for remuneration of Executive Directors
// Denotes a scale break. All bar chart scales start from zero. We use a scale break where charts of a different magnitude, but the same unit of measurement, are presented alongside each other.
肿瘤学
澳门第一赌城在线娱乐正在引领肿瘤学的一场革命，重新定义癌症治疗.
Our ambition is to follow the science to discover, 开发和提供改变生活的治疗方法，增加治愈的可能性.
澳门第一赌城在线娱乐努力突破科学的界限，改变医学实践，改变癌症患者的生活.
BioPharmaceuticals
澳门第一赌城在线娱乐希望改善数十亿慢性病患者的生活, enabling them to live life without limits.
澳门第一赌城在线娱乐的目标是阻止这些经常退化的进步, debilitating 和 life-threatening conditions, achieve remission 和, 有一天,, 治愈他们.
澳门第一赌城在线娱乐负责心血管、肾脏 & Metabolism 和 呼吸 & 免疫学.
罕见的疾病
2021年7月21日，澳门第一赌城在线娱乐完成了对Alexion Pharmaceuticals, Inc .的收购. 并创建了澳门在线赌城娱乐罕见病领域，这是澳门第一赌城在线娱乐公司的一个新领域.
澳门第一赌城在线娱乐的使命是改变受罕见疾病和毁灭性疾病影响的人们的生活. By underst和ing 病人’ unique needs, we can research 和 develop innovative medicines, support access 和 advocate for the rare disease community.
新型冠状病毒肺炎
We are working to defeat the 新型冠状病毒肺炎 p和emic.
与 Vaxzevria 和 Evusheld，澳门第一赌城在线娱乐正在为全球公共卫生作出重大贡献.
AstraZeneca 和 our global partners released for supply 2.5 billion vaccine doses to over 180 countries. Approximately two-thirds of these went to LMICs, 2021年，通过全球获取疫苗机制向130个国家提供了2.47亿多剂疫苗.
可持续性 Highlights
澳门第一赌城在线娱乐的目标是以对社会产生积极影响的方式利用科学和创新的力量, 病人, healthcare systems 和 the environment, through actions for the long term.
通过澳门第一赌城在线娱乐10亿美元的“雄心零碳”旗舰计划, 澳门第一赌城在线娱乐的目标是到2026年将全球运营的温室气体排放量减少98%，到2030年将整个价值链的足迹减少一半, on the way to a 90% reduction by 2045.
Access to healthcare
澳门第一赌城在线娱乐正在努力实现一个人人都能获得可持续卫生解决方案，获得改变生活的治疗和护理的未来.
Achievements in 2021:
31.0m
超过199,自2010年以来培训了1 000名卫生保健工作者和其他人员，通过获得卫生保健方案惠及了3 100多万人.
Environmental protection
澳门第一赌城在线娱乐的目标是通过在所有活动和产品中尽量减少对环境的影响来展示全球领导地位. Becoming increasingly circular, we are designing out waste 和 pollution, keeping products 和 materials in use, 和 maximising resource efficiency.
Achievements in 2021:
59%
自2015年以来，第1类和第2类温室气体排放量减少59%.
Ethics 和 transparency
澳门第一赌城在线娱乐力求创造积极的社会影响，并将道德行为融入澳门第一赌城在线娱乐所有的业务活动中, markets 和 value chain. We do this by promoting ethical, 在澳门第一赌城在线娱乐公司以及所有合作伙伴和供应商之间制定透明和包容的政策.
Achievements in 2021:
48.1%
48.1%的高级中层及以上管理职位由女性担任.
Net cash flow from operating activities
$6.0bn •
Up 24% at actual rate of exchange to $6.0bn
报告每股收益
$0.08
Down 97% at actual rate of exchange to $0.08
(down 84% at CER)
核心每股收益
$5.29 •
Up 32% at actual rate of exchange to $5.29
(CER上涨37%)
• Used for remuneration of Executive Directors
// Denotes a scale break. All bar chart scales start from zero. We use a scale break where charts of a different magnitude, but the same unit of measurement, are presented alongside each other.
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